Corneal neovascularization: a modern view of molecular mechanisms and methods of therapy

This review provides a detailed summary of the issues etiology, pathogenesis and molecular mechanisms corneal neovascularization. Signaling molecules involved in process neovasculogenesis, as well their antagonists, antiangiogenic factors, are described. The role signaling proteins VEGF, MMP receptors modern targets therapy is described on basis series clinical studies. potentials gene bioengineering promising method treating neovascularization presented.